Hyaluronan in Cancer Biology Stern 1e 2009 - Academic Press ISBN 9780123741783 - R$ 163,00 Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered normal cellular processes for their own survival and spread. There are also parallels between cancer and wound healing, cancer occasionally being defined as a wound that does not heal. Faça seu pedido !!

Molecular Pathology - The Molecular Basis of Human Disease Coleman and Tsongalis 1e 2009 - Academic Press ISBN 9780123744197 - R$ 203,00 Most "pathology" textbooks cover diseases and disease processes from the perspective of description (what does it look like and what are its characteristics), risk factors, disease-causing agents, and to some extent, cellular mechanisms. However, these books typically contain very sparse coverage (if any at all) of molecular mechanisms of disease. The reason for this is partially historical - most major forms of disease have been known for a long time, but the molecular basis of these diseases are not always known or have been elucidated only recently. Nevertheless, our overall understanding of the molecular and genetic mechanisms of the pathogenesis of most major human diseases has been advancing at a significant pace over the last two decades. As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, there is a need for a new textbook where molecular mechanisms represent the focus. Faça seu pedido !!

Genetic Diseases of the Kidney Lifton et al 1e 2008 - Academic Press ISBN 9780124498518 - R$ 325,00 Genetic approaches have revolutionized our understanding of the fundamental causes of human disease by permitting the identification of specific genes in which variation causes or contributes to susceptibility to, or protection from, disease. More than 2000 disease genes have been identified in the last 20 years, providing important new insight into the pathophysiology of diseases in every field of medicine. Genetic Diseases of the Kidney offers expert insight into the role of genetic abnormalities in the pathogenesis of abnormal kidney function and kidney disease. Genetic abnormalities are carefully presented within the appropriate physiologic context, so that readers will understand not only which genes are linked to which diseases but also which pathways lead from a genetic “disturbance” to the systemic appearance of disease. Faça seu pedido !!

Textbook of Nephro-Endocrinology Singh and Williams 1e 2008 - Academic Press ISBN 9780123738707 - R$ 335,00 The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers both researchers and clinicians expert, gold-standard analysis of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoprosis, and, hypoparathyroidism. Faça seu pedido!!

Hematopathology, Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches Naeim et al 1e 2008 - Academic Press ISBN 9780123706072 - R$ 305,00 This comprehensive, full color hematopathology reference book emphasizes immunophenotpic features, cytogenetic studies, and diagnostic molecular aspects. Hematopathology begins with introductions to morphologic evaluation of the hematopoietic tissues and principles of immunophenotyping, cytogenetics and molecular studies followed by chapters dedicated to different types of hematologic disorders. Each chapter starts with a basic overview of hematopathlogy followed by a comprehensive review of immunophenotypic, cytogenetic and molecular findings. The text is balanced with large numbers of full color images, graphs, charts, and tables to assist the reader in understanding these highly technical issues. Faça seu pedido !!

Asthma and COPD - Basic Mechanisms and Clinical Management Barnes et al 2e 2008 - Academic Press ISBN 9780123740014 - R$ 305,00 The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. Faça seu pedido !!

Medical Cell Biology Goodman 3e 2007 - Academic Press ISBN 9780123704580 - R$ 86,00 This is the third edition of Dr. Steven Goodman's highly popular and successful Medical Cell Biology textbook. Dr. Goodman is a respected expert in this field and led the Association of Anatomy, Cell Biology and Neurobiology Chairs in drafting the Cell Biology portion of the United States and Canadian Curriculum in the Anatomical Sciences. This book, with its National Board type questions, is specifically designed to prepare students for this exam. This textbook covers Medical Cell Biology in a succinct manner, focusing on aspects which are important to students in medical, dental, veterinary and pre-health majors at both the undergraduate and advanced degree level. Faça seu pedido !!

Diagnostic Atlas of Gastroesophageal Reflux Disease - A New Histology-based Method Chandrasoma 1e 2007 - Academic Press ISBN 9780123736055 - R$ 348,00 A short, well illustrated "how to" book the Diagnostic Atlas of Gastroesophageal Reflux Disease offers detailed methods of exactly how physicians, pathologists and gastroenterologists should approach a patient they encounter clinically or how they should approach a biopsy. This full color atlas presents practical diagnostic guidelines for the management of patients with gastroesophageal reflux disease. It incorporates the newest data to provide guidelines to the gastroenterologist and pathologist about accurate diagnostic criteria for reflux, interpretation of endoscopic landmarks, protocol for biopsy, and interpretation of histology. Faça seu pedido !!